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1

Involvement of Histone H1.2 in Apoptosis Induced by DNA Double-Strand Breaks

Akimitsu Konishi, Shigeomi Shimizu, Junko Hirota, Toshifumi Takao, Yuhong Fan, Yosuke Matsuoka, Lilin Zhang, Yoshihiro Yoneda, Yoshitaka Fujii, Arthur I. Skoultchi, Yoshihide Tsujimoto

Journal:

Year:

2003

Language:

english

File:

PDF, 885 KB

english, 2003

2

Direct Thioamination of Arynes via Reaction with Sulfilimines and Migratory N -Arylation

Yoshida, Suguru, Yano, Takahisa, Misawa, Yoshihiro, Sugimura, Yasuyuki, Igawa, Kazunobu, Shimizu, Shigeomi, Tomooka, Katsuhiko, Hosoya, Takamitsu

Journal:

Journal of the American Chemical Society

Year:

2015

Language:

english

File:

PDF, 1.56 MB

english, 2015

3

Identification of a novel compound that inhibits both mitochondria-mediated necrosis and apoptosis

Arakawa, Satoko, Nakanomyo, Ikuko, Kudo-Sakamoto, Yoko, Akazawa, Hiroshi, Komuro, Issei, Shimizu, Shigeomi

Journal:

Biochemical and Biophysical Research Communications

Year:

2015

Language:

english

File:

PDF, 2.73 MB

english, 2015

4

Hypertrophy and Unconventional Cell Division of Hepatocytes Underlie Liver Regeneration

Yuichiro Miyaoka, Kazuki Ebato, Hidenori Kato, Satoko Arakawa, Shigeomi Shimizu, Atsushi Miyajima

Journal:

Current Biology

Year:

2012

Language:

english

File:

PDF, 2.31 MB

english, 2012

5

p53 Inhibits Vascular Endothelial Growth Factor Expression in Solid Tumor

Yasuhiko Yoshioka, Shigeomi Shimizu, Toshinori Ito, Masahiko Taniguchi, Masaya Nomura, Toshirou Nishida, Yoshiki Sawa

Journal:

Journal of Surgical Research

Year:

2012

Language:

english

File:

PDF, 1.08 MB

english, 2012

6

Delayed-onset caspase-dependent massive hepatocyte apoptosis upon fas activation in bak/bax-deficient mice

Hayato Hikita, Tetsuo Takehara, Takahiro Kodama, Satoshi Shimizu, Minoru Shigekawa, Atsushi Hosui, Takuya Miyagi, Tomohide Tatsumi, Hisashi Ishida, Wei Li, Tatsuya Kanto, Naoki Hiramatsu, Shigeomi Shi

Journal:

Year:

2011

Language:

english

File:

PDF, 1.09 MB

english, 2011

7

Omi / HtrA2 is relevant to the selective vulnerability of striatal neurons in Huntington’s disease

Reina Inagaki, Kazuhiko Tagawa, Mei-Ling Qi, Yasushi Enokido, Hikaru Ito, Takuya Tamura, Shigeomi Shimizu, Kityomitsu Oyanagi, Nobutaka Arai, Ichiro Kanazawa, Erich E Wanker, Hitoshi Okazawa

Journal:

European Journal of Neuroscience

Year:

2008

Language:

english

File:

PDF, 1.11 MB

english, 2008

8

Bax and Bcl-xL independently regulate apoptotic changes of yeast mitochondria that require VDAC but not adenine nucleotide translocator

Shimizu, Shigeomi, Shinohara, Yasuo, Tsujimoto, Yoshihide

Journal:

Year:

2000

Language:

english

File:

PDF, 267 KB

english, 2000

9

xCT deficiency accelerates chemically induced tumorigenesis

Ami Nabeyama, Ai Kurita, Kenichi Asano, Yasunobu Miyake, Takuwa Yasuda, Ikuo Miura, Gen Nishitai, Satoko Arakawa, Shigeomi Shimizu, Shigeharu Wakana, Hisahiro Yoshida, Masato Tanaka and Michael Karin

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.58 MB

english, 2010

10

Autophagy controls centrosome number by degrading Cep63

Watanabe, Yuichiro, Honda, Shinya, Konishi, Akimitsu, Arakawa, Satoko, Murohashi, Michiko, Yamaguchi, Hirofumi, Torii, Satoru, Tanabe, Minoru, Tanaka, Shinji, Warabi, Eiji, Shimizu, Shigeomi

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 2.15 MB

english, 2016

11

Bcl-2 family: Life-or-death switch

Yoshihide Tsujimoto, Shigeomi Shimizu

Journal:

Year:

2000

Language:

english

File:

PDF, 165 KB

english, 2000

12

Pro-apoptotic actions of 53BP2 in a human pancreatic cancer cell line

Kajino, Shinichi, Teranishi, Futoshi, Takahashi, Naoko, Ohara, Hirotaka, Shimizu, Shigeomi, Itoh, Makoto, Okamoto, Takashi

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 195 KB

english, 2000

13

Autophagy takes an alternative pathway

Shimizu, Shigeomi, Arakawa, Satoko, Nishida, Yuya

Journal:

Year:

2010

Language:

english

File:

PDF, 301 KB

english, 2010

14

TRF2 Interacts with Core Histones to Stabilize Chromosome Ends

Konishi, Akimitsu, Izumi, Takashi, Shimizu, Shigeomi

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 5.14 MB

english, 2016

15

Functional Modification of Cytochrome c by Peroxynitrite in an Electron Transfer Reaction.

NAKAGAWA, Hidehiko, OHSHIMA, Yukiko, TAKUSAGAWA, Mitsuko, IKOTA, Nobuo, TAKAHASHI, Yutaka, SHIMIZU, Shigeomi, OZAWA, Toshihiko

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

2001

Language:

english

File:

PDF, 91 KB

english, 2001

16

Involvement of phosphorylation of ULK1 in alternative autophagy

Torii, Satoru, Shimizu, Shigeomi

Journal:

Year:

2020

File:

PDF, 730 KB

2020

17

10.1038/20959

Tsujimoto, Yoshihide, Shimizu, Shigeomi, Narita, Masashi, Tsujimoto, Yoshihide

Journal:

Year:

1999

Language:

english

File:

PDF, 379 KB

english, 1999

18

Cyclophilin D-dependent mitochondrial permeability transition is not involved in neurodegeneration in mnd2 mutant mice

Kan Ideguchi, Shigeomi Shimizu, Meinoshin Okumura, Yoshihide Tsujimoto

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 380 KB

english, 2010

19

Association Between Autophagy and Neurodegenerative Diseases

Fujikake, Nobuhiro, Shin, Minkyoung, Shimizu, Shigeomi

Journal:

Frontiers in Neuroscience

Year:

2018

Language:

english

File:

PDF, 778 KB

english, 2018

20

Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes

Shimizu, Shigeomi, Kanaseki, Toku, Mizushima, Noboru, Mizuta, Takeshi, Arakawa-Kobayashi, Satoko, Thompson, Craig B., Tsujimoto, Yoshihide

Journal:

Nature Cell Biology

Year:

2004

Language:

english

File:

PDF, 1.31 MB

english, 2004

21

Human gelsolin prevents apoptosis by inhibiting apoptotic mitochondrial changes via closing VDAC

Kusano, Hajime, Shimizu, Shigeomi, Koya, Richard Chikara, Fujita, Hisakazu, Kamada, Shinji, Kuzumaki, Noboru, Tsujimoto, Yoshihide

Journal:

Year:

2000

Language:

english

File:

PDF, 228 KB

english, 2000

22

Changes in Biliary Glutathione Level during Ischemia-Reperfusion of Rat Liver

Masahiro Fujikawa, Wataru Kamiike, Nobutaka Hatanaka, Shigeomi Shimizu, Akinori Akashi, Masahiko Miyata, Kazuhei Kurosawa, Yukuo Yoshida, Kunio Tagawa, Hikaru Matsuda

Journal:

Journal of Surgical Research

Year:

1994

File:

PDF, 287 KB

1994

23

S2-1 Function of BCL-2 and ice family proteases in cell death

Shimizu Shigeomi, Eguchi Yutaka, Tsujimoto Yoshihide

Journal:

Neuroscience Research

Year:

1996

Language:

english

File:

PDF, 44 KB

english, 1996

24

10.1038/35037638

Shimizu, Shigeomi, Narita, Masashi, Tsujimoto, Yoshihide

Journal:

Year:

2000

Language:

english

File:

PDF, 854 KB

english, 2000

25

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

Nakagawa, Takashi, Shimizu, Shigeomi, Watanabe, Tetsuya, Yamaguchi, Osamu, Otsu, Kinya, Yamagata, Hirotaka, Inohara, Hidenori, Kubo, Takeshi, Tsujimoto, Yoshihide

Journal:

Year:

2005

Language:

english

File:

PDF, 625 KB

english, 2005

26

Activation of mitochondrial voltage-dependent anion channel by apro-apoptotic BH3-only protein Bim

Sugiyama, Tomoyasu, Shimizu, Shigeomi, Matsuoka, Yosuke, Yoneda, Yoshihiro, Tsujimoto, Yoshihide

Journal:

Year:

2002

Language:

english

File:

PDF, 400 KB

english, 2002

27

Ca2+ Release from Mitochondria Induces Cytosolic Enzyme Leakage in Anoxic Liver

Nobutaka Hatanaka, Wataru Kamiike, Shigeomi Shimizu, Masahiko Miyata, Toru Inoue, Yukuo Yoshida, Kunio Tagawa, Hikaru Matsuda

Journal:

Journal of Surgical Research

Year:

1995

File:

PDF, 351 KB

1995

28

Intrinsic Autophagy Is Required for the Maintenance of Intestinal Stem Cells and for Irradiation-Induced Intestinal Regeneration

Asano, Jumpei, Sato, Taku, Ichinose, Shizuko, Kajita, Mihoko, Onai, Nobuyuki, Shimizu, Shigeomi, Ohteki, Toshiaki

Journal:

Year:

2017

Language:

english

File:

PDF, 3.02 MB

english, 2017

29

The ceramide analogue N-(1-hydroxy-3-morpholino-1-phenylpropan-2-yl)decanamide induces large lipid droplet accumulation and highlights the effect of LAMP-2 deficiency on lipid droplet degradation

Kato, Yuji, Arakawa, Satoko, Terasawa, Kazue, Inokuchi, Jin-ichi, Iwata, Takanori, Shimizu, Shigeomi, Watabe, Tetsuro, Hara-Yokoyama, Miki

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2020

File:

PDF, 6.30 MB

2020

30

10.1038/35037645

Shimizu, Shigeomi, Narita, Masashi, Tsujimoto, Yoshihide

Journal:

Year:

2000

Language:

english

File:

PDF, 308 KB

english, 2000

31

Involvement of Beclin 1 in Engulfment of Apoptotic Cells

Konishi, Akimitsu, Arakawa, Satoko, Yue, Zhenyu, Shimizu, Shigeomi

Journal:

Journal of Biological Chemistry

Year:

2012

Language:

english

File:

PDF, 4.44 MB

english, 2012

32

Autophagy involvement in oncogenesis

Torii, Satoru, Honda, Shinya, Murohashi, Michiko, Yamaguchi, Hirofumi, Shimizu, Shigeomi

Journal:

Year:

2020

File:

PDF, 908 KB

2020

33

The role of Cyclophilin D in learning and memory

Akihiro Mouri, Yukihiro Noda, Shigeomi Shimizu, Yoshihide Tsujimoto, Toshitaka Nabeshima

Journal:

Year:

2010

Language:

english

File:

PDF, 542 KB

english, 2010

34

Discovery of Atg5/Atg7-independent alternative macroautophagy

Nishida, Yuya, Arakawa, Satoko, Fujitani, Kenji, Yamaguchi, Hirofumi, Mizuta, Takeshi, Kanaseki, Toku, Komatsu, Masaaki, Otsu, Kinya, Tsujimoto, Yoshihide, Shimizu, Shigeomi

Journal:

Year:

2009

Language:

english

File:

PDF, 1018 KB

english, 2009

35

The voltage-dependent anion channel: an essential player in apoptosis

Yoshihide Tsujimoto, Shigeomi Shimizu

Journal:

Year:

2002

Language:

english

File:

PDF, 127 KB

english, 2002

36

Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes

Honda, Shinya, Arakawa, Satoko, Nishida, Yuya, Yamaguchi, Hirofumi, Ishii, Eiichi, Shimizu, Shigeomi

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 7.37 MB

english, 2014

37

Role of Atg5-dependent cell death in the embryonic development of Bax/Bak double-knockout mice

Arakawa, Satoko, Tsujioka, Masatsune, Yoshida, Tatsushi, Tajima-Sakurai, Hajime, Nishida, Yuya, Matsuoka, Yosuke, Yoshino, Ikuyo, Tsujimoto, Yoshihide, Shimizu, Shigeomi

Journal:

Cell Death & Differentiation

Year:

2017

Language:

english

File:

PDF, 5.28 MB

english, 2017

38

Rhodium-catalyzed odorless synthesis of diaryl sulfides from borylarenes and S-aryl thiosulfonates

Kanemoto, Kazuya, Sugimura, Yasuyuki, Shimizu, Shigeomi, Yoshida, Suguru, Hosoya, Takamitsu

Journal:

Chemical Communications

Year:

2017

Language:

english

File:

PDF, 2.80 MB

english, 2017

39

Multicentric Carcinoma in situ Occurring in a Villous Adenoma of the Appendix

Furutani, Yasuhiro, Nakao, Kazuyasu, Hamaji, Masayasu, Nakahara, Masaaki, Shimizu, Shigeomi, Tsujimoto, Masahiko

Journal:

Digestive Surgery

Year:

1991

Language:

english

File:

PDF, 1.45 MB

english, 1991

40

10.1038/35037650

Shimizu, Shigeomi, Narita, Masashi, Tsujimoto, Yoshihide

Journal:

Year:

2000

Language:

english

File:

PDF, 274 KB

english, 2000

41

Shigella Targets Epithelial Tricellular Junctions and Uses a Noncanonical Clathrin-Dependent Endocytic Pathway to Spread Between Cells

Makoto Fukumatsu, Michinaga Ogawa, Satoko Arakawa, Masato Suzuki, Kazuhisa Nakayama, Shigeomi Shimizu, Minsoo Kim, Hitomi Mimuro, Chihiro Sasakawa

Journal:

Cell Host & Microbe

Year:

2012

Language:

english

File:

PDF, 2.26 MB

english, 2012

42

In Situ Characterization of Bak Clusters Responsible for Cell Death Using Single Molecule Localization Microscopy

Nasu, Yusuke, Benke, Alexander, Arakawa, Satoko, Yoshida, Go J., Kawamura, Genki, Manley, Suliana, Shimizu, Shigeomi, Ozawa, Takeaki

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.53 MB

english, 2016

43

Beclin 1 regulates recycling endosome and is required for skin development in mice

Noguchi, Saori, Honda, Shinya, Saitoh, Tatsuya, Matsumura, Hiroyuki, Nishimura, Emi, Akira, Shizuo, Shimizu, Shigeomi

Journal:

Communications Biology

Year:

2019

Language:

english

File:

PDF, 4.11 MB

english, 2019

44

BH4-domain peptide from Bcl-xL exerts anti-apoptotic activity in vivo

Sugioka, Rie, Shimizu, Shigeomi, Funatsu, Toshihiro, Tamagawa, Hiroshi, Sawa, Yoshiki, Kawakami, Toru, Tsujimoto, Yoshihide

Journal:

Year:

2003

Language:

english

File:

PDF, 315 KB

english, 2003

45

Prevention of Hypoxic Liver Cell Necrosis byin VivoHumanbcl-2Gene Transfection

Kazuo Yamabe, Shigeomi Shimizu, Wataru Kamiike, Satoshi Waguri, Yutaka Eguchi, Jun-ichi Hasegawa, Shin-ichiro Okuno, Yasuhiko Yoshioka, Toshinori Ito, Yoshiki Sawa, Yasuo Uchiyama, Yoshihide Tsujimoto

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 4.90 MB

english, 1998

46

Preparation of connexin43-integrated giant Liposomes by a baculovirus expression–liposome fusion method

Koki Kamiya, Kanta Tsumoto, Satoko Arakawa, Shigeomi Shimizu, Ikuo Morita, Tetsuro Yoshimura, Kazunari Akiyoshi

Journal:

Biotechnology and Bioengineering

Year:

2010

Language:

english

File:

PDF, 2.97 MB

english, 2010

47

10.1038/35037655

Shimizu, Shigeomi, Narita, Masashi, Tsujimoto, Yoshihide

Journal:

Year:

2000

Language:

english

File:

PDF, 1.12 MB

english, 2000

48

Transformation of an antimicrobial peptide into a plasma membrane-permeable, mitochondria-targeted peptide via the substitution of lysine with arginine

Nakase, Ikuhiko, Okumura, Shinya, Katayama, Sayaka, Hirose, Hisaaki, Pujals, Sílvia, Yamaguchi, Hirofumi, Arakawa, Satoko, Shimizu, Shigeomi, Futaki, Shiroh

Journal:

Chemical Communications

Year:

2012

Language:

english

File:

PDF, 647 KB

english, 2012

49

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging || Mammalian Autophagy Can Occur Through an Atg5/Atg7-Independent Pathway

Shimizu, Shigeomi

Year:

2014

Language:

english

File:

PDF, 1.41 MB

english, 2014

50

10.1038/35037658

Shimizu, Shigeomi, Narita, Masashi, Tsujimoto, Yoshihide

Journal:

Year:

2000

Language:

english

File:

PDF, 999 KB

english, 2000

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